منابع مشابه
Sea Anemone (Cnidaria, Anthozoa, Actiniaria) Toxins: An Overview
The Cnidaria phylum includes organisms that are among the most venomous animals. The Anthozoa class includes sea anemones, hard corals, soft corals and sea pens. The composition of cnidarian venoms is not known in detail, but they appear to contain a variety of compounds. Currently around 250 of those compounds have been identified (peptides, proteins, enzymes and proteinase inhibitors) and non...
متن کاملRefined structure in solution of the sea anemone neurotoxin ShI.
A high resolution structure in solution has been determined for the polypeptide neurotoxin I, from the sea anemone Stichodactyla helianthus, using NMR data, distance geometry calculations, and refinement by back-calculation of two-dimensional nuclear Overhauser enhancement (NOE) spectra. A set of 913 distance constraints derived from NOEs was used, together with a large set of lower distance bo...
متن کاملIsolation and partial characterization of three lethal and hemolytic toxins from the sea anemone Actinia cari.
Three lethal and hemolytic toxins, caritoxin I, II and III were isolated from the sea anemone Actinia cari. Following controlled autolysis, tentacles were strained through a nylon sieve and thus a crude extract was obtained. The toxins were further purified by Sephadex G-75 gel chromatography. All three toxins which were eluted at the same peak, were separated by ion-exchange chromatography on ...
متن کاملKalicludines and kaliseptine. Two different classes of sea anemone toxins for voltage sensitive K+ channels.
New peptides have been isolated from the sea anemone Anemonia sulcata which inhibit competitively the binding of 125I-dendrotoxin I (a classical ligand for K+ channel) to rat brain membranes and behave as blockers of voltage-sensitive K+ channels. Sea anemone kalicludines are 58-59-amino acid peptides cross-linked with three disulfide bridges. They are structurally homologous both to dendrotoxi...
متن کاملIsolation and characterization of three lethal and hemolytic toxins from the sea anemone Actinia equina L.
Lethal and hemolytic toxins were purified by acetone precipitation, Sephadex G-50, CM-cellulose and CM-Sephadex column chromatography from the tentacles and bodies of the sea anemone Actinia equina. The isolated toxins, with a mol. wt of 19,000 determined by SDS-polyacrylamide gel electrophoresis, differed only slightly in amino acid composition and had a high tryptophan content. The isoelectri...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1982
ISSN: 0014-5793
DOI: 10.1016/0014-5793(82)80030-6